cefotetan
Sign in to saveAlso known as ICI-156834, (6R,7S)-7-[4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido]-7-methoxy-3-{[(1-methyl-1H-tetrazol-5- yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid
Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often grouped together with second-generation cephalosporins and has a similar antibacterial spectrum, but with additional anti-anaerobe coverage.
Research
864 papers- Cefotetan.2006
- Cefotetan: a review of the microbiologic properties and antimicrobial spectrum.American journal of surgery · 1988
- Cefotetan. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.Drugs · 1985
- Clinical pharmacokinetics of cefotetan.Clinical pharmacokinetics · 1994
- Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway.Acta biochimica et biophysica Sinica · 2022
via PubMed
Wikidata facts
- Subclass of
- cephalosporin antibiotic
- Mass
- 575.0021445040001
Show 9 more facts
- discoverer or inventor
- Astellas Pharma
- chemical formula
- C₁₇H₁₇N₇O₈S₄
- medical condition treated
- staphylococcal infection
- World Health Organisation international non-proprietary name
- cefotetan
- defined daily dose
- 4
- subject has role
- antibiotic
- isomeric SMILES
- CO[C@]1(NC(=O)C2SC(=C(C(=O)N)C(=O)O)S2)[C@H]3SCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C
- stylized name
- cefoTEtan
- canonical SMILES
- COC1(NC(=O)C2SC(=C(C(N)=O)C(=O)O)S2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC21
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Adverse effects
- Spectrum of bacterial susceptibility
- References
- External links
{{Drugbox | Verifiedfields = changed | verifiedrevid = 401948686 | IUPAC_name = (7S)-7-{[4-(1-amino-3-hydroxy-1,3-dioxopropan-2-ylidene)1,3-dithietane-2-carbonyl]amino}-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = Cefotetan.svg | image_class = skin-invert-image | width = 250
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = B | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = Rx-only | legal_status = | routes_of_administration = Injection
Excerpted from Wikipedia’s “cefotetan” article, available under the CC BY-SA 4.0 licence.
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