ceftibuten

Also known as 7432-S, Cedax, Seftem, SCH-39720, cis-Ceftibuten, Ceftibuteno, (+)-(6R,7R)-7-((Z)-2-(2-amino-4-Thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, Ceftibutenum

Ceftibuten is a third-generation cephalosporin antibiotic. It is an orally administered agent, with two dosage forms, capsule or oral suspension. It is marketed by Pernix Therapeutics under the trade name Cedax.

Chemical data

Formula: C15H14N4O6S2
Molecular weight: 410.4 g/mol
IUPAC name: (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\CC(=O)O)/C3=CSC(=N3)N)C(=O)O
InChIKey: UNJFKXSSGBWRBZ-BJCIPQKHSA-N
XLogP: -0.3
Polar surface area: 216 Å²
H-bond donors: 4
H-bond acceptors: 10
Formal charge: 0

via PubChem

Research

366 papers

Ceftibuten.2006
Ceftibuten.Indian pediatrics · 1999
[Ceftibuten].The Japanese journal of antibiotics · 1993
Ceftibuten: an overview.Pharmacotherapy · 1997
Ceftibuten pharmacokinetics and pharmacodynamics. Focus on paediatric use.Clinical pharmacokinetics · 1994

via PubMed

Wikidata facts

Mass: 410.035476

Show 6 more facts

chemical formula: C₁₅H₁₄N₄O₆S₂
World Health Organisation international non-proprietary name: ceftibuten
isomeric SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\CC(=O)O)/C3=CSC(=N3)N)C(=O)O
canonical SMILES: C1C=C(N2C(S1)C(C2=O)NC(=O)C(=CCC(=O)O)C3=CSC(=N3)N)C(=O)O
defined daily dose: 0.4
Commons category: Ceftibuten

Sources (3)

via Wikidata · CC0

~1 min read