File:Cefalexin.svg · Wikimedia Commons · See Wikimedia Commons
cephalexin
Sign in to saveAlso known as cefalexin, Ceporex®, Keflex®, CEX, Ceporexin, Cepastar, Celexin, Cepexin
Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to other agents within this class, including intravenous cefazolin, but can be taken by mouth.
Chemical data
- Formula
- C16H17N3O4S
- Molecular weight
- 347.4 g/mol
- IUPAC name
- (6R,7R)-7-[[(2R)-2-azaniumyl-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- SMILES
- CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)[NH3+])SC1)C(=O)[O-]
- InChIKey
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N
- XLogP
- 1.3
- Polar surface area
- 142 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- cephalosporin antibiotic
- Mass
- 347.093977
- Has use
- medication
Show 9 more facts
- route of administration
- intravenous infusion and defusion
- chemical formula
- C₁₆H₁₇N₃O₄S
- medical condition treated
- cellulitis
- isomeric SMILES
- CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)SC1)C(=O)O
- canonical SMILES
- CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=CC=C3)N)SC1)C(=O)O
- Commons category
- Cefalexin
- defined daily dose
- 2
- subject has role
- bactericide
- found in taxon
- Streptomyces
via Wikidata · CC0
~8 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Pregnancy and breastfeeding
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Society and culture
- Brand names
- Veterinary uses
- Dogs
- References
Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to other agents within this class, including intravenous cefazolin, but can be taken by mouth.
Cefalexin can treat certain bacterial infections, including those of the middle ear, bone and joint, skin, and urinary tract. It may also be used for certain types of pneumonia and strep throat and to prevent bacterial endocarditis. Cefalexin is not effective against infections caused by methicillin-resistant Staphylococcus aureus (MRSA), most Enterococcus, or Pseudomonas. Like other antibiotics, cefalexin cannot treat viral infections, such as the flu, common cold or acute bronchitis. Cefalexin can be used in those who have mild or moderate allergies to penicillin. However, it is not recommended in those with severe penicillin allergies.
Excerpted from Wikipedia’s “cephalexin” article, available under the CC BY-SA 4.0 licence.