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chlorethoxyfos

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EntityQ421438· pop 11· linked from 381 articles

chlorethoxyfos

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Also known as O,O-diethyl O-(1,2,2,2-tetrachloroethyl) thiophosphate, Chlorethoxyphos, Chloroethoxyfos

Chlorethoxyfos ('''O,O-diethyl-O-(1,2,2,2-tetrachloroethyl)phosphorothioate''') is an organophosphate acetylcholinesterase inhibitor used as an insecticide. It is registered for the control of corn rootworms, wireworms, cutworms, seed corn maggot, white grubs and symphylans on corn. The insecticide is sold under the trade name Fortress by E.I. du Pont de Nemours & Company.

Chemical data

Formula
C6H11Cl4O3PS
Molecular weight
336 g/mol
IUPAC name
diethoxy-sulfanylidene-(1,2,2,2-tetrachloroethoxy)-lambda5-phosphane
SMILES
CCOP(=S)(OCC)OC(C(Cl)(Cl)Cl)Cl
InChIKey
XFDJMIHUAHSGKG-UHFFFAOYSA-N
XLogP
4.6
Polar surface area
59.8 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
333.89206256200004
Show 3 more facts
chemical formula
C₆H₁₁Cl₄O₃PS
canonical SMILES
CCOP(=S)(OCC)OC(C(Cl)(Cl)Cl)Cl
Commons category
Chlorethoxyfos
Sources (2)

via Wikidata · CC0

~15 min read

Encyclopedic overview

15 sections
Contents
  • History
  • Mechanism of action
  • Metabolism
  • Synthesis
  • Efficacy and effects
  • Ecotoxicology
  • Effects on animals
  • Effects on the nervous system
  • Nonspecific toxic effects
  • Mammalian toxicology
  • Toxicity
  • Symptoms
  • Treatment
  • First aid
  • References

Chlorethoxyfos ('''O,O-diethyl-O-(1,2,2,2-tetrachloroethyl)phosphorothioate') is an organophosphate acetylcholinesterase inhibitor used as an insecticide. It is registered for the control of corn rootworms, wireworms, cutworms, seed corn maggot, white grubs and symphylans on corn. The insecticide is sold under the trade name Fortress by E.I. du Pont de Nemours & Company.

Annual domestic usage of chlorethoxyfos is estimated to range from 8,500 to 17,800 pounds of active ingredient for approximately 37,000 to 122,000 acres treated. Approximately 1% of all corn acreage is treated.

Excerpted from Wikipedia’s “chlorethoxyfos” article, available under the CC BY-SA 4.0 licence.

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