minaprine
Sign in to saveAlso known as CB-30038, AGR-1240, 4-methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin, 4-{2-[(4-Methyl-6-phenyl-3-pyridazinyl)amino]ethyl}morpholine, N-(4-methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine
Minaprine (INN, USAN, BAN; brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.
Research
131 papers- Cholinomimetic activities of minaprine.Naunyn-Schmiedeberg's archives of pharmacology · 1989
- [Minaprine].Revista de medicina de la Universidad de Navarra · 1984
- Minaprine, a new drug with antidepressant properties.Drugs under experimental and clinical research · 1985
- Novel aminopyridazine derivative of minaprine modified by radiolysis presents potent anti-inflammatory effects in LPS-stimulated RAW 264.7 and DH82 macrophage cells.Scientific reports · 2023
- Minaprine for senile dementia.Lancet (London, England) · 1985
via PubMed
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Minaprine (INN, USAN, BAN; brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.
A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. It has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
Excerpted from Wikipedia’s “minaprine” article, available under the CC BY-SA 4.0 licence.
Available in 11 languages
via Wikidata sitelinks · CC0