cinchonism
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Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark. Quinine and its derivatives are used medically to treat malaria and lupus erythematosus. In much smaller amounts, quinine is an ingredient of tonic drinks, acting as a bittering agent. Cinchonism can occur from therapeutic doses of quinine, either from one or several large doses. Quinidine (a Class 1A anti-arrhythmic) can also cause cinchonism symptoms to develop with as little as a single dose.
In the Vinony graph
Within Vinony's link graph, cinchonism is referenced by 97 other articles, and connects out to lichen planus, otoscope and pesticide poisoning.
It sits within the topics Poisoning by drugs, medicaments and biological substances and Quinine.
Its subject is documented across 9 Wikipedia language editions.
Wikidata facts
- Instance of
- symptom or sign
Show 3 more facts
- health specialty
- emergency medicine
- ICPC 2 ID
- A84
- has cause
- quinine
Sources (1)
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Encyclopedic overview
3 sectionsContents
- Signs and symptoms
- References
- External links
Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark. Quinine and its derivatives are used medically to treat malaria and lupus erythematosus. In much smaller amounts, quinine is an ingredient of tonic drinks, acting as a bittering agent. Cinchonism can occur from therapeutic doses of quinine, either from one or several large doses. Quinidine (a Class 1A anti-arrhythmic) can also cause cinchonism symptoms to develop with as little as a single dose.
==Signs and symptoms== Signs and symptoms of mild cinchonism (which may occur from standard therapeutic doses of quinine) include flushed and sweaty skin, ringing of the ears (tinnitus), blurred vision, impaired hearing, confusion, reversible high-frequency hearing loss, headache, abdominal pain, rashes, drug-induced lichenoid reaction (lichenoid photosensitivity), vertigo, dizziness, nausea, vomiting and diarrhea.
Excerpted from Wikipedia’s “cinchonism” article, available under the CC BY-SA 4.0 licence.