CLOCK
Sign in to saveCLOCK (backronym for circadian locomotor output cycles kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor that is known to affect both the persistence and period of circadian rhythms.
Wikidata facts
- Instance of
- gene
- Image
- Circadian CLOCK protein.png
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- P703
- Homo sapiens
- P1057
- human chromosome 4
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Article
15 sectionsContents
- Discovery
- Function
- Role in other feedback loops
- Evolution
- Phylogeny
- Variant allele forms
- Role in mammalian evolution
- Mutants
- ''Drosophila''
- Mice
- Observed effects
- See also
- References
- Further reading
- External links
CLOCK (backronym for circadian locomotor output cycles kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor that is known to affect both the persistence and period of circadian rhythms.
Research shows that the gene plays a major role as an activator of downstream elements in the pathway critical to the generation of circadian rhythms.