condensin complex
Sign in to save450px|thumb|Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome condensation and segregation during mitosis and meiosis (Figure 1). Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.
Article
26 sectionsContents
- Subunit composition and phylogeny
- Eukaryotic types
- Prokaryotic types
- Molecular structures
- Molecular activities
- DNA compaction
- DNA supercoiling
- DNA loop extrusion
- DNA loop capture
- Chromosome assembly and reconstitution
- Condensin I vs condensin II
- Mathematical modeling and computer simulations
- Functions in chromosome assembly and segregation
- Mitosis
- Meiosis
- Chromosomal functions outside of mitosis or meiosis
- Regulation
- Spatiotemporal regulation
- Regulation by post-translational modifications
- Regulation by Short Linear Motifs (SLiMs)
- Regulation by proteolysis
- Relevance to diseases
- Evolutionary implications
- See also
- References
- External links
450px|thumb|Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome condensation and segregation during mitosis and meiosis (Figure 1). Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.
== Subunit composition and phylogeny ==