AURKB
Sign in to saveAlso known as AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12
protein-coding gene in the species Homo sapiens
Gene data
AURKB- Name
- aurora kinase B
- Type
- protein-coding
- Position
- 8,204,335–8,210,638 (−)
- Aliases
- AIK2, AIM-1, AIM1, ARK-2, ARK2, AurB, IPL1, PPP1R48, STK-1, STK12
- Ensembl
- ENSG00000178999
- RefSeq RNA
- NM_001256834.3, NM_001284526.2, NM_001313950.2, NM_001313951.1, NM_001313952.2
- RefSeq protein
- NP_001243763.1, NP_001271455.1, NP_001300879.1, NP_001300880.1, NP_001300881.1
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015].
Gene Ontology
Biological process
Molecular function
Pathways
Amplification of signal from the kinetochoresAmplification of signal from unattached kinetochores via a MAD2 inhibitory signalSignal TransductionCell CycleAPC/C-mediated degradation of cell cycle proteinsAPC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1Signaling by Rho GTPasesRHO GTPase EffectorsGeneric Transcription PathwayGeneric Transcription Pathway
via MyGene.info
Gene · Ensembl
aurora kinase B
- Symbol
- AURKB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:8,204,335-8,210,638
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 55807
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9212
- chromosome
- human chromosome 17
- genomic start
- 8108056
- genomic end
- 8113918
- Commons category
- Aurora kinase B
- cytogenetic location
- 17p13.1
- expressed in
- bone marrow
via Wikidata · CC0