spermidine
Sign in to saveSpermidine is a polyamine compound () originally isolated from semen and also found in ribosomes and living tissues and has various metabolic functions in organisms.
Article
7 sectionsContents
- Function
- Biosynthesis
- Biochemical actions
- Sources
- Uses
- References
- External links
Spermidine is a polyamine compound () originally isolated from semen and also found in ribosomes and living tissues and has various metabolic functions in organisms.
==Function== Spermidine synchronizes an array of biological processes, (such as Ca2+, Na+, K+ -ATPase) thus maintaining membrane potential and controlling intracellular pH and volume. Spermidine regulates biological processes, such as Ca2+ influx by glutamatergic N-methyl-D-aspartate receptor (NMDA receptor), which has been associated with nitric oxide synthase (NOS) and cGMP/PKG pathway activation and a decrease of Na+,K+-ATPase activity in cerebral cortex synaptosomes.