File:Lupusfoto.jpg · Wikimedia Commons · See Wikimedia Commons
systemic lupus erythematosus
Sign in to saveAlso known as SLE, lupus, Lupus Erythematosus, systemic, SLE - Lupus Erythematosus, systemic, disseminated lupus erythematosus
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed ch
Systemic lupus erythematosus (SLE), commonly called lupus, is an autoimmune disease where the body's immune system mistakenly attacks its own healthy tissue throughout the body, causing symptoms that range from mild to severe including joint pain and swelling, fever, chest pain, hair loss, mouth ulcers, fatigue, and a facial rash. It matters because the disease typically involves cycles of flares and remissions that can significantly affect a person's quality of life, and it can be particularly severe in children.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Medical condition (new).name
- Lupus
- Medical condition (new).synonyms
- Systemic lupus erythematosus (SLE)
- Medical condition (new).image
- Lupusfoto.jpg
- Medical condition (new).caption
- Young woman with the distinctive butterfly rash that many individuals with lupus experience
- Medical condition (new).field
- Rheumatology
- Medical condition (new).symptoms
- Painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, red rash
- Medical condition (new).onset
- 15–45 years of age
- Medical condition (new).duration
- Long term
- Medical condition (new).causes
- Unclear
- Medical condition (new).diagnosis
- Based on symptoms and blood tests
- Medical condition (new).medication
- NSAIDs, corticosteroids, immunosuppressants, hydroxychloroquine, methotrexate
- Medical condition (new).prognosis
- 15 year survival ~80%
- Medical condition (new).frequency
- 2–7 per 10,000
via Wikipedia infobox
Research
94,081 papersvia PubMed
Wikidata facts
- Instance of
- symptom or sign
- Subclass of
- disease
- Named after
- Canis lupus
- Image
- Lupusfoto.jpg
Show 11 more facts
- Commons category
- Systemic lupus erythematosus
- NCI Thesaurus ID
- C3201
- health specialty
- dermatology
- ICPC 2 ID
- L99
- drug or therapy used for treatment
- hydroxychloroquine
- described by source
- Brockhaus and Efron Encyclopedic Dictionary
- on focus list of Wikimedia project
- WikiProject Medicine
- exact match
- www.orpha.net/ORDO/Orphanet_536
- risk factor
- female
- ICD-9-CM
- 710.0
- external data available at URL
- www.nanbyou.or.jp/entry/53
Sources (9)
via Wikidata · CC0
~61 min read
Encyclopedic overview
53 sectionsContents
- Signs and symptoms
- Skin
- Muscles and bones
- Blood
- Heart
- Lungs
- Kidneys
- Neuropsychiatric
- Eyes
- Reproductive
- Systemic
- Causes
- Vitamin D deficiency
- Genetics
- Drug-induced SLE
- Epstein-Barr virus
- Non-systemic forms of lupus
- Pathophysiology
- Cell death signaling
- Clearance deficiency
- Germinal centers
- Anti-nRNP autoimmunity
- Others
- Diagnosis
- Laboratory tests
- Diagnostic criteria
- Criteria
- Criteria for individual diagnosis
- Treatment
- Medications
- Disease-modifying antirheumatic drugs
- Immunosuppressive drugs
- Analgesia
- Intravenous immunoglobulins (IVIGs)
- Lifestyle changes
- Kidney transplantation
- Antiphospholipid syndrome
- Management of pregnancy
- Prognosis
- Epidemiology
- Race
- Sex
- Changing rate of disease
- History
- Etymology
- Classical period
- Neoclassical period
- Modern period
- Research
- Famous cases
- See also
- References
- External links
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus.
Lupus is Latin for "wolf": the disease was so-named in the 13th century as the rash was thought to resemble a wolf's bite.
Excerpted from Wikipedia’s “systemic lupus erythematosus” article, available under the CC BY-SA 4.0 licence.
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