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systemic lupus erythematosus

File:Lupusfoto.jpg · Wikimedia Commons · See Wikimedia Commons

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systemic lupus erythematosus

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Also known as SLE, lupus, Lupus Erythematosus, systemic, SLE - Lupus Erythematosus, systemic, disseminated lupus erythematosus

Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed ch

AI overview

Systemic lupus erythematosus (SLE), commonly called lupus, is an autoimmune disease where the body's immune system mistakenly attacks its own healthy tissue throughout the body, causing symptoms that range from mild to severe including joint pain and swelling, fever, chest pain, hair loss, mouth ulcers, fatigue, and a facial rash. It matters because the disease typically involves cycles of flares and remissions that can significantly affect a person's quality of life, and it can be particularly severe in children.

AI-generated from the Wikipedia summary — may contain errors.

Key facts

Medical condition (new).name
Lupus
Medical condition (new).synonyms
Systemic lupus erythematosus (SLE)
Medical condition (new).image
Lupusfoto.jpg
Medical condition (new).caption
Young woman with the distinctive butterfly rash that many individuals with lupus experience
Medical condition (new).field
Rheumatology
Medical condition (new).symptoms
Painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, red rash
Medical condition (new).onset
15–45 years of age
Medical condition (new).duration
Long term
Medical condition (new).causes
Unclear
Medical condition (new).diagnosis
Based on symptoms and blood tests
Medical condition (new).medication
NSAIDs, corticosteroids, immunosuppressants, hydroxychloroquine, methotrexate
Medical condition (new).prognosis
15 year survival ~80%
Medical condition (new).frequency
2–7 per 10,000

via Wikipedia infobox

Research

94,081 papers

via PubMed

Wikidata facts

Instance of
symptom or sign
Subclass of
disease
Named after
Canis lupus
Image
Lupusfoto.jpg
Show 11 more facts
Commons category
Systemic lupus erythematosus
NCI Thesaurus ID
C3201
health specialty
dermatology
ICPC 2 ID
L99
drug or therapy used for treatment
hydroxychloroquine
on focus list of Wikimedia project
WikiProject Medicine
risk factor
female
ICD-9-CM
710.0
external data available at URL
www.nanbyou.or.jp/entry/53
Sources (9)

via Wikidata · CC0

~61 min read

Encyclopedic overview

53 sections
Contents
  • Signs and symptoms
  • Skin
  • Muscles and bones
  • Blood
  • Heart
  • Lungs
  • Kidneys
  • Neuropsychiatric
  • Eyes
  • Reproductive
  • Systemic
  • Causes
  • Vitamin D deficiency
  • Genetics
  • Drug-induced SLE
  • Epstein-Barr virus
  • Non-systemic forms of lupus
  • Pathophysiology
  • Cell death signaling
  • Clearance deficiency
  • Germinal centers
  • Anti-nRNP autoimmunity
  • Others
  • Diagnosis
  • Laboratory tests
  • Diagnostic criteria
  • Criteria
  • Criteria for individual diagnosis
  • Treatment
  • Medications
  • Disease-modifying antirheumatic drugs
  • Immunosuppressive drugs
  • Analgesia
  • Intravenous immunoglobulins (IVIGs)
  • Lifestyle changes
  • Kidney transplantation
  • Antiphospholipid syndrome
  • Management of pregnancy
  • Prognosis
  • Epidemiology
  • Race
  • Sex
  • Changing rate of disease
  • History
  • Etymology
  • Classical period
  • Neoclassical period
  • Modern period
  • Research
  • Famous cases
  • See also
  • References
  • External links

Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus.

Lupus is Latin for "wolf": the disease was so-named in the 13th century as the rash was thought to resemble a wolf's bite.

Excerpted from Wikipedia’s “systemic lupus erythematosus” article, available under the CC BY-SA 4.0 licence.

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