autoimmune disease

Also known as hypersensitivity reaction type II disease, autoimmune hypersensitivity disease, autoimmune diseases

disorders of adaptive immune system

AI overview

An autoimmune disease occurs when your body's immune system mistakenly attacks its own cells and tissues instead of protecting you from harmful invaders like bacteria and viruses. These disorders matter because they can cause chronic inflammation and damage to various parts of your body, affecting your quality of life and requiring ongoing medical management.

AI-generated from the Wikipedia summary — may contain errors.

Research

694,003 papers

Stress as a trigger of autoimmune disease.ReviewAutoimmunity reviews · 2008Stojanovich L, Marisavljevich DDOI: 10.1016/j.autrev.2007.11.007
Pregnancy and Autoimmune Disease.ReviewDeutsches Arzteblatt international · 2022Merz WM, Fischer-Betz R, Hellwig K et al.DOI: 10.3238/arztebl.m2021.0353
Gender differences in autoimmune disease.ReviewFrontiers in neuroendocrinology · 2014Ngo ST, Steyn FJ, McCombe PADOI: 10.1016/j.yfrne.2014.04.004
Autoimmune disease: a view of epigenetics and therapeutic targeting.ReviewFrontiers in immunology · 2024Mu S, Wang W, Liu Q et al.DOI: 10.3389/fimmu.2024.1482728
Inborn Errors of Immunity and Autoimmune Disease.ReviewThe journal of allergy and clinical immunology. In practice · 2023Gray PE, David CDOI: 10.1016/j.jaip.2023.04.018
Sex Hormones in Acquired Immunity and Autoimmune Disease.ReviewFrontiers in immunology · 2018Moulton VRDOI: 10.3389/fimmu.2018.02279
Pathogen infection and autoimmune disease.Clinical and experimental immunology · 2019Christen UDOI: 10.1111/cei.13239
Autoimmune disease.ReviewNature biotechnology · 2000

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Wikidata facts

Subclass of: primary immunodeficiency disease
Image: Warm autoimmune hemolytic anemia.jpg

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health specialty: rheumatology
afflicts: immunity
Commons category: Autoimmune diseases and disorders
has effect: rheumatoid arthritis
topic's main category: Category:Autoimmune diseases
drug or therapy used for treatment: methylprednisolone
exact match: identifiers.org/doid/DOID:417
ICD-9-CM: 720
has cause: type II hypersensitivity
topic has template: Template:Hypersensitivity disease by cause
manifestation of: autoimmunity
on focus list of Wikimedia project: WikiProject Medicine
NCI Thesaurus ID: C2889

Sources (7)

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Encyclopedic overview

An autoimmune disease is a condition causing disease that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific evidence suggesting the existence of potentially more than 100 distinct conditions. Nearly any body part can be involved.

Autoimmune diseases are a separate class from autoinflammatory diseases. Both are characterized by an immune system malfunction which may cause similar symptoms, such as rash, swelling, or fatigue, but the cardinal cause or mechanism of the diseases is different. A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system.

Excerpted from Wikipedia’s “autoimmune disease” article, available under the CC BY-SA 4.0 licence.

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