autoimmune disease
disorders of adaptive immune system
AI overview
An autoimmune disease occurs when your body's immune system mistakenly attacks its own cells and tissues instead of protecting you from harmful invaders like bacteria and viruses. These disorders matter because they can cause chronic inflammation and damage to various parts of your body, affecting your quality of life and requiring ongoing medical management.
AI-generated from the Wikipedia summary — may contain errors.
Research
693,875 papers- Stress as a trigger of autoimmune disease.Autoimmunity reviews · 2008
- Pregnancy and Autoimmune Disease.Deutsches Arzteblatt international · 2022
- Gender differences in autoimmune disease.Frontiers in neuroendocrinology · 2014
- Autoimmune disease: a view of epigenetics and therapeutic targeting.Frontiers in immunology · 2024
- Inborn Errors of Immunity and Autoimmune Disease.The journal of allergy and clinical immunology. In practice · 2023
via PubMed
Article
An autoimmune disease is a condition causing disease that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific evidence suggesting the existence of potentially more than 100 distinct conditions. Nearly any body part can be involved.
Autoimmune diseases are a separate class from autoinflammatory diseases. Both are characterized by an immune system malfunction which may cause similar symptoms, such as rash, swelling, or fatigue, but the cardinal cause or mechanism of the diseases is different. A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system.