Quinone oxidoreductase is an enzyme that in humans is encoded by the CRYZ gene.
Quinone oxidoreductase is an enzyme that in humans is encoded by the CRYZ gene.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).