cymarin

Also known as cymarine

Cymarin (or cymarine) is a cardiac glycoside. Plants of the genus Apocynum, including Apocynum cannabinum and Apocynum venetum, contain cymarin. Cymarin is a cardiac glycoside and an anti-arrhythmia and cardiotonic agent.

Research

126 papers

Translation of paired box 6 (PAX6) mRNA is IRES-mediated and inhibited by cymarin in breast cancer cells.Genes & genetic systems · 2023
TUMOR INHIBITORS. IV. APOCANNOSIDE AND CYMARIN, THE CYTOTOXIC PRINCIPLES OF APOCYNUM CANNABINUM L.Journal of medicinal chemistry · 1964
Large-Scale Screening of Natural Products Transactivating Peroxisome Proliferator-Activated Receptor α Identifies 9S-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid and Cymarin as Potential Compounds Capable of Increasing Apolipoprotein A-I Transcription in Human Liver Cells.Lipids · 2018
Isolation of cymarin from Adonis aestivalis.Lloydia · 1973
Unveiling the mechanism of action of Cymarin in combating breast cancer: An integrated computational analysis.Journal of molecular graphics & modelling · 2026

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Wikidata facts

Mass: 548.298532988

Show 5 more facts

chemical formula: C₃₀H₄₄O₉
isomeric SMILES: C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2CC[C@@]3([C@H]4CC[C@@]5([C@H](CC[C@@]5([C@@H]4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)C=O)OC)O
canonical SMILES: O=CC12CCC(OC3OC(C)C(O)C(OC)C3)CC2(O)CCC4C1CCC5(C)C(C6=CC(=O)OC6)CCC45O
Commons category: Cymarin
defined daily dose: 2.5

Sources (3)

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