Structure via PubChem · Public domain (PubChem)
peruvoside
Sign in to savePeruvoside (or cannogenin thevetoside) is a cardiac glycoside for heart failure.
In the Vinony graph
Vinony's link graph records 27 inbound references to peruvoside, and connects out to medication, circulatory system and digital object identifier.
It sits within the topics Alcohols, Aldehydes and Cardenolides.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C30H44O9
- Molecular weight
- 548.7 g/mol
- IUPAC name
- (3S,5R,8R,9S,10R,13R,14S,17R)-3-[(2R,3S,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
- SMILES
- C[C@H]1[C@@H]([C@H]([C@@H]([C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3CC[C@]5([C@@]4(CC[C@@H]5C6=CC(=O)OC6)O)C)C=O)O)OC)O
- InChIKey
- PMTSPAGBAFCORP-HBUONDEYSA-N
- XLogP
- 0.7
- Polar surface area
- 132 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
55 papers- Peruvoside targets apoptosis and autophagy through MAPK Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways in human cancers.Life sciences · 2020
- Peruvoside is a novel Src inhibitor that suppresses NSCLC cell growth and motility by downregulating multiple Src-EGFR-related pathways.American journal of cancer research · 2022
- The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses.Acta pharmaceutica Sinica. B · 2023
- Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death.Molecules (Basel, Switzerland) · 2016
- Observations on the effects of peruvoside.The Indian journal of medical research · 1971
via PubMed
Wikidata facts
- Subclass of
- aldehydes
- Mass
- 548.299
Show 4 more facts
- canonical SMILES
- CC1C(C(C(C(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CCC5C6=CC(=O)OC6)O)C)C=O)O)OC)O
- isomeric SMILES
- C[C@H]1[C@@H]([C@H]([C@@H]([C@@H](O1)O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]4[C@@H]3CC[C@]5([C@@]4(CC[C@@H]5C6=CC(=O)OC6)O)C)C=O)O)OC)O
- chemical formula
- C₃₀H₄₄O₉
- subject has role
- cardiotonic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Peruvoside (or cannogenin thevetoside) is a cardiac glycoside for heart failure.
It is derived from Cascabela thevetia (Thevetia neriifolia).
Excerpted from Wikipedia’s “peruvoside” article, available under the CC BY-SA 4.0 licence.