metildigoxin

Also known as methyldigoxin

Metildigoxin (INN, or medigoxin BAN, or methyldigoxin) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). The substance is closely related to digoxin; it differs from the latter only by an O-methyl group on the terminal monosaccharide.

Research

168 papers

Medigoxin.Lancet (London, England) · 1978
Extrarenal clearance, distribution volume, and elimination rate of digoxin and metildigoxin in anuric patients.International journal of clinical pharmacology, therapy, and toxicology · 1981
Pharmacokinetics of metildigoxin and digoxin in geriatric patients with normal and elevated serum creatinine levels.Clinical pharmacokinetics · 1981
Changes in metildigoxin pharmacokinetics in cirrhosis of the liver: a comparison with beta-acetyldigoxin.International journal of clinical pharmacology, therapy, and toxicology · 1984
Effect of metildigoxin (beta-methyldigoxin) on congestive heart failure as evaluated by multiclinical double blind study.Japanese heart journal · 1980

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Wikidata facts

Mass: 794.445

Show 4 more facts

canonical SMILES: CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)OC
chemical formula: C₄₂H₆₆O₁₄
isomeric SMILES: C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)OC
defined daily dose: 0.2

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References

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