cytosine

Chemical data

Formula

C4H5N3O

Molecular weight

111.1 g/mol

IUPAC name

6-amino-1H-pyrimidin-2-one

SMILES

C1=C(NC(=O)N=C1)N

InChIKey

OPTASPLRGRRNAP-UHFFFAOYSA-N

XLogP

-1.7

Polar surface area

67.5 Ų

H-bond donors

2

H-bond acceptors

2

Formal charge

0

via PubChem

• High-precision cytosine base editors by evolving nucleic-acid-recognition hotspots in deaminase.Nature biotechnology · 2026Wu Y, Xiao YL, Tang WDOI: 10.1038/s41587-025-02678-w
• Cytosine Methylation Studies in Patients with Diabetic Kidney Disease.ReviewCurrent diabetes reports · 2019Aranyi T, Susztak KDOI: 10.1007/s11892-019-1214-6
• Cytosine base editors with increased PAM and deaminase motif flexibility for gene editing in zebrafish.Nature communications · 2024Zhang Y, Liu Y, Qin W et al.DOI: 10.1038/s41467-024-53735-y
• Cytosine methylation and DNA repair.ReviewCurrent topics in microbiology and immunology · 2006Walsh CP, Xu GLDOI: 10.1007/3-540-31390-7_11
• Hydroxymethyl cytosine marks in the human mitochondrial genome are dynamic in nature.Mitochondrion · 2016Ghosh S, Sengupta S, Scaria VDOI: 10.1016/j.mito.2016.01.003
• A new method for sequencing DNA.Proceedings of the National Academy of Sciences of the United States of America · 1977Maxam AM, Gilbert WDOI: 10.1073/pnas.74.2.560
• Phage arabinosyl-hydroxy-cytosine DNA modifications result in distinct evasion and sensitivity responses to phage defense systems.Cell host & microbe · 2025Mahler M, Cui L, Smith LM et al.DOI: 10.1016/j.chom.2025.06.005
• Antigen Retrieval for Immunostaining of Modified Cytosine Species.Methods in molecular biology (Clifton, N.J.) · 2021Celik-Uzuner SDOI: 10.1007/978-1-0716-0876-0_18

via PubMed