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دی-ای‌اوپی‌ای

Structure via PubChem · Public domain (PubChem)

EntityQ3738328· pop 9· linked from 1,389 articles

دی-ای‌اوپی‌ای

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Also known as dopa D-form, (+)-3-(3,4-dihydroxyphenyl)alanine, (+)-3,4-dihydroxyphenylalanine, D-3-(3,4-dihydroxyphenyl)alanine, D-3,4-dihydroxyphenylalanine, 3-hydroxy-D-tyrosine, 3,4-dihydroxy-D-phenylalanine

-DOPA dextrodopa) is similar to (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction. Whereas is moderately effective in the treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, is biologically inactive.

Chemical data

Formula
C9H11NO4
Molecular weight
197.19 g/mol
IUPAC name
(2R)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
SMILES
C1=CC(=C(C=C1C[C@H](C(=O)O)N)O)O
InChIKey
WTDRDQBEARUVNC-ZCFIWIBFSA-N
XLogP
-2.7
Polar surface area
104 Ų
H-bond donors
4
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
197.068808
Show 5 more facts
stereoisomer of
levodopa
chemical formula
C₉H₁₁NO₄
found in taxon
Portulaca grandiflora
isomeric SMILES
C1=CC(=C(C=C1C[C@H](C(=O)O)N)O)O
canonical SMILES
C1=CC(=C(C=C1CC(C(=O)O)N)O)O
Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0