Structure via PubChem · Public domain (PubChem)
octodrine
Sign in to saveOctodrine, also known as dimethylhexylamine (DMHA) and sold under the brand name Vaporpac among others, is a sympathomimetic and stimulant medication that was formerly used in the treatment of hypotension (low blood pressure).
Chemical data
- Formula
- C8H19N
- Molecular weight
- 129.24 g/mol
- IUPAC name
- 6-methylheptan-2-amine
- SMILES
- CC(C)CCCC(C)N
- InChIKey
- QNIVIMYXGGFTAK-UHFFFAOYSA-N
- XLogP
- 2.3
- Polar surface area
- 26 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 129.152
Show 3 more facts
- chemical formula
- C₈H₁₉N
- canonical SMILES
- CC(C)CCCC(C)N
- Commons category
- Octodrine
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
9 sectionsContents
- Side effects
- Pharmacology
- Pharmacokinetics
- Chemistry
- Related compounds
- Society and culture
- Names
- As an unsafe dietary ingredient
- References
Octodrine, also known as dimethylhexylamine (DMHA) and sold under the brand name Vaporpac among others, is a sympathomimetic and stimulant medication that was formerly used in the treatment of hypotension (low blood pressure).
It has been studied in a dozen animal studies from the 1940s through the 1970s. These studies found that octodrine can increase blood pressure and cardiac output in animals. The drug was previously approved for use by the Food and Drug Administration (FDA) as an inhalant (i.e., Vaporpac and Tickle Tackle Inhaler) and in Germany as an oral medication as part of a multi-component medication (i.e., Ambredin and Ordinal), but is no longer available.
Excerpted from Wikipedia’s “octodrine” article, available under the CC BY-SA 4.0 licence.