Structure via PubChem · Public domain (PubChem)
dantrona
Sign in to saveAlso known as Dorbane, Istizin, 1,8-dihydroxy-9,10-anthracenedione, 1,8-dihydroxyanthra-9,10-quinone, Danthron, 1,8-dihydroxy-9,10-anthraquinone, 1,8-Dihydroxyanthraquinone, Chrysazin
composto químico
Chemical data
- Formula
- C14H8O4
- Molecular weight
- 240.21 g/mol
- IUPAC name
- 1,8-dihydroxyanthracene-9,10-dione
- SMILES
- C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
- InChIKey
- QBPFLULOKWLNNW-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 74.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- Constipation
via ChEMBL · EBI
Research
194 papers- Danthron attenuates experimental atherosclerosis by targeting foam cell formation.Experimental physiology · 2021
- Danthron.Report on carcinogens : carcinogen profiles · 2011
- Laxatives: replacing danthron.Drug and therapeutics bulletin · 1988
- Danthron suppresses autophagy and sensitizes pancreatic cancer cells to doxorubicin.Toxicology in vitro : an international journal published in association with BIBRA · 2019
- Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties.Antioxidants (Basel, Switzerland) · 2023
via PubMed
Wikidata facts
- Mass
- 240.042
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₄H₈O₄
- canonical SMILES
- C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
- World Health Organisation international non-proprietary name
- dantron
- found in taxon
- Asphodelus fistulosus
- defined daily dose
- 50
- subject has role
- carcinogen
via Wikidata · CC0
Article · Português
Dantrona (Crisacina; 1,8-Dihidroxiantraquinona) é um fármaco utilizado em medicamentos como laxante.
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 9 languages
via Wikidata sitelinks · CC0