1,8-Dihydroxyanthrachinon

Also known as Dorbane, Istizin, 1,8-dihydroxy-9,10-anthracenedione, 1,8-dihydroxyanthra-9,10-quinone, Danthron, 1,8-dihydroxy-9,10-anthraquinone, 1,8-Dihydroxyanthraquinone, Chrysazin

chemische Verbindung

In the Vinony graph

Vinony's link graph records 67 inbound references to 1,8-Dihydroxyanthrachinon, and connects out to laxative, United States and United Kingdom.

Vinony files it under 3-Hydroxypropenals within hydroxyquinones, Dihydroxyanthraquinones and Drugboxes which contain changes to verified fields.

Vinony links it to 9 Wikipedia language editions.

Chemical data

Formula: C14H8O4
Molecular weight: 240.21 g/mol
IUPAC name: 1,8-dihydroxyanthracene-9,10-dione
SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
InChIKey: QBPFLULOKWLNNW-UHFFFAOYSA-N
XLogP: 3.2
Polar surface area: 74.6 Å²
H-bond donors: 2
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Withdrawn

Max clinical phase: Approved
Molecule type: Small molecule
Indications: Constipation

via ChEMBL · EBI

Research

194 papers

Danthron attenuates experimental atherosclerosis by targeting foam cell formation.Experimental physiology · 2021
Danthron.Report on carcinogens : carcinogen profiles · 2011
Laxatives: replacing danthron.Drug and therapeutics bulletin · 1988
Danthron suppresses autophagy and sensitizes pancreatic cancer cells to doxorubicin.Toxicology in vitro : an international journal published in association with BIBRA · 2019
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties.Antioxidants (Basel, Switzerland) · 2023

via PubMed

Wikidata facts

Mass: 240.042
Has use: medication

Show 6 more facts

chemical formula: C₁₄H₈O₄
canonical SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
World Health Organisation international non-proprietary name: dantron
found in taxon: Asphodelus fistulosus
defined daily dose: 50
subject has role: carcinogen

Sources (4)

via Wikidata · CC0

Article · Deutsch

1,8-Dihydroxyanthrachinon, auch unter dem Namen Chrysazin oder Danthron bekannt, ist eine organische Verbindung aus der Stoffgruppe der Anthrachinone (genauer der Dihydroxyanthrachinone).

Abstract from DBpedia / Wikipedia · CC BY-SA