dantrolene

Key facts

Drug.Verifiedfields

changed

Drug.verifiedrevid

459436942

Drug.image

Dantrolene.svg

Drug.image_class

skin-invert-image

Drug.alt

Structural formula of dantrolene

Drug.width

250

Drug.image2

Dantrolene 3D spacefill.png

Drug.image_class2

bg-transparent

Drug.alt2

Space-filling model of the dantrolene molecule

Drug.tradename

Dantrium, Revonto, Ryanodex

Drug.MedlinePlus

a682576

Drug.DailyMedID

Dantrolene

Drug.pregnancy_AU

B2

Drug.routes_of_administration

By mouth, intravenous

Drug.ATC_prefix

M03

Drug.ATC_suffix

CA01

Drug.legal_CA

Rx-only

Drug.legal_UK

POM

via Wikipedia infobox

Chemical data

Formula

C14H10N4O5

Molecular weight

314.25 g/mol

IUPAC name

1-[[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione

SMILES

C1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]

InChIKey

OZOMQRBLCMDCEG-UHFFFAOYSA-N

XLogP

1.7

Polar surface area

121 Ų

H-bond donors

1

H-bond acceptors

6

Formal charge

0

via PubChem

• Dantrolene.Canadian Anaesthetists' Society journal · 1984
• [Dantrolene. Pharmacological and therapeutic aspects].Der Anaesthesist · 2003
• Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2020
• Approaches to Optimizing Dantrolene Neuroprotection for the Treatment of Alzheimer's Disease.Current Alzheimer research · 2020
• Dantrolene in the treatment of MDMA-related hyperpyrexia: a systematic review.CJEM · 2010

via PubMed