DAPK1
Sign in to saveAlso known as DAPK, death associated protein kinase 1, ROCO3
Death-associated protein kinase 1 is an enzyme that in humans is encoded by the DAPK1 gene.
Gene data
DAPK1- Name
- death associated protein kinase 1
- Type
- protein-coding
- Position
- 87,497,203–87,709,073 (+)
- Aliases
- DAPK, ROCO3
- Ensembl
- ENSG00000196730
- RefSeq RNA
- NM_001288729.2, NM_001288730.2, NM_001288731.2, NM_004938.4, XM_005251757.5
- RefSeq protein
- NP_001275658.1, NP_001275659.1, NP_001275660.1, NP_004929.2, XP_005251814.1
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
death associated protein kinase 1
- Symbol
- DAPK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:87,497,203-87,709,073
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- As a drug target
- References
- Further reading
Death-associated protein kinase 1 is an enzyme that in humans is encoded by the DAPK1 gene.
== Function ==
Excerpted from Wikipedia’s “DAPK1” article, available under the CC BY-SA 4.0 licence.