Structure via PubChem · Public domain (PubChem)
داپسون
Sign in to saveAlso known as 4,4'-Diaminodiphenylsulfone, DDS, 4,4'-Sulfonyldianilin, 4,4'-sulfonyldianiline, DADPS, P,P-Sulphonylbisbenzamine, Bis(P-aminophenyl) sulfone, P,P'-diaminodiphenyl sulfone
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 460773489
- Drug.IUPAC_name
- 4-[(4-aminobenzene)sulfonyl]aniline
- Drug.image
- Dapsone.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Dapsone3d.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Aczone, others
- Drug.MedlinePlus
- a682128
- Drug.DailyMedID
- Dapsone
- Drug.pregnancy_US
- C
- Drug.routes_of_administration
- By mouth, topical
- Drug.legal_AU
- S4
- Drug.legal_US
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.bioavailability
- 70 to 80%
- Drug.protein_bound
- 70 to 90%
- Drug.metabolism
- Liver (mostly CYP2E1-mediated)
via Wikipedia infobox
Chemical data
- Formula
- C12H12N2O2S
- Molecular weight
- 248.3 g/mol
- IUPAC name
- 4-(4-aminophenyl)sulfonylaniline
- SMILES
- C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
- InChIKey
- MQJKPEGWNLWLTK-UHFFFAOYSA-N
- XLogP
- 1
- Polar surface area
- 94.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
7,492 papers- Dapsone Use in Dermatology.American journal of clinical dermatology · 2024
- Dapsone.Dermatology online journal · 2002
- Dapsone for acne: Still in use after half a century!Journal of cosmetic dermatology · 2021
- Dapsone-associated fixed drug eruption.Expert review of clinical pharmacology · 2017
- Dapsone-induced methemoglobinemia.The Annals of pharmacotherapy · 1998
via PubMed