Structure via PubChem · Public domain (PubChem)
delafloxacin
Sign in to saveDelafloxacin sold under the brand name Baxdela among others, is a fluoroquinolone antibiotic used to treat acute bacterial skin and skin structure infections. It was developed by Melinta Therapeutics.
Key facts
- Drug.image
- Delafloxacin.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.tradename
- Baxdela, others
- Drug.DailyMedID
- Delafloxacin
- Drug.routes_of_administration
- By mouth, intravenous injection
- Drug.ATC_prefix
- J01
- Drug.ATC_suffix
- MA23
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.index2_label
- as salt
- Drug.CAS_number
- 189279-58-1
- Drug.CAS_supplemental
- 352458-37-8 (meglumine)
- Drug.PubChem
- 487101
- Drug.DrugBank
- DB11943
- Drug.ChemSpiderID
- 427049
via Wikipedia infobox
Chemical data
- Formula
- C18H12ClF3N4O4
- Molecular weight
- 440.8 g/mol
- IUPAC name
- 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid
- SMILES
- C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=C(C=C(C(=N4)N)F)F)F)O
- InChIKey
- DYDCPNMLZGFQTM-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 120 Ų
- H-bond donors
- 3
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2017
- Admin. routes
- oral, parenteral
- Indications
- gonorrhea, liver disease, bacterial pneumonia, infection
via ChEMBL · EBI
Research
286 papers- Delafloxacin.2012
- Delafloxacin.2006
- Delafloxacin: A Review in Community-Acquired Pneumonia.Drugs · 2022
- Delafloxacin for the treatment of adult patients with community-acquired bacterial pneumonia.Expert review of anti-infective therapy · 2022
- Delafloxacin: First Global Approval.Drugs · 2017
via PubMed
Wikidata facts
- Subclass of
- quinolone antibiotic
- Mass
- 440.05
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₈H₁₂ClF₃N₄O₄
- canonical SMILES
- C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=NC(=C(C=C4F)F)N)F)O
- NCI Thesaurus ID
- C87390
- Commons category
- Delafloxacin
via Wikidata · CC0
~6 min read
Encyclopedic overview
7 sectionsContents
- Medical use
- Adverse effects
- Interactions
- Pharmacology
- Chemistry
- History
- References
Delafloxacin sold under the brand name Baxdela among others, is a fluoroquinolone antibiotic used to treat acute bacterial skin and skin structure infections. It was developed by Melinta Therapeutics.
==Medical use== Delafloxacin is indicated to treat adults with acute bacterial skin and skin structure infections (ABSSSI) caused by designated susceptible bacteria or adults with community-acquired bacterial pneumonia (CABP) caused by designated susceptible bacteria.
Excerpted from Wikipedia’s “delafloxacin” article, available under the CC BY-SA 4.0 licence.