Structure via PubChem · Public domain (PubChem)
pazufloxacin
Sign in to savePazufloxacin (INN) is a fluoroquinolone antibiotic. It is sold in Japan under the brand names Pasil and Pazucross.
Chemical data
- Formula
- C16H15FN2O4
- Molecular weight
- 318.3 g/mol
- IUPAC name
- (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
- SMILES
- C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O
- InChIKey
- XAGMUUZPGZWTRP-ZETCQYMHSA-N
- XLogP
- -0.8
- Polar surface area
- 92.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- Otitis media, bacterial conjunctivitis, bacterial disease
via ChEMBL · EBI
Research
165 papers- Pazufloxacin.The Journal of the Association of Physicians of India · 2009
- Pazufloxacin Toyama Chemical Co.Current opinion in investigational drugs (London, England : 2000) · 2000
- Concentration-Dependent Activity of Pazufloxacin against Pseudomonas aeruginosa: An In Vivo Pharmacokinetic/Pharmacodynamic Study.Antibiotics (Basel, Switzerland) · 2022
- [Pharmacological properties and expected clinical role of an injectable new quinolone antibiotic, pazufloxacin mesilate].Nihon yakurigaku zasshi. Folia pharmacologica Japonica · 2003
- [Quantitative determination of pazufloxacin using water-soluble quantum dots as fluorescent probes].Guang pu xue yu guang pu fen xi = Guang pu · 2008
via PubMed
Wikidata facts
- Subclass of
- carboxylic acid
- Mass
- 318.102
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₆H₁₅FN₂O₄
- canonical SMILES
- CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O
- isomeric SMILES
- C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O
- Commons category
- Pazufloxacin
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Pazufloxacin (INN) is a fluoroquinolone antibiotic. It is sold in Japan under the brand names Pasil and Pazucross.
== See also == Quinolone antibiotic
Excerpted from Wikipedia’s “pazufloxacin” article, available under the CC BY-SA 4.0 licence.
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