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dibrompropamidine
Sign in to saveDibrompropamidine is an antiseptic and disinfectant. As dibrompropamidine isethionate, it is used in eyedrops and ointment for the treatment of minor eye and eyelid infections in adults and children. In the UK, such preparations are sold under the brand names Brolene (Aventis Pharma), Golden Eye (Typharm Ltd), and Brulidine (Manx Healthcare).
Chemical data
- Formula
- C17H18Br2N4O2
- Molecular weight
- 470.2 g/mol
- IUPAC name
- 3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
- SMILES
- C1=CC(=C(C=C1C(=N)N)Br)OCCCOC2=C(C=C(C=C2)C(=N)N)Br
- InChIKey
- GMJFVGRUYJHMCO-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 118 Ų
- H-bond donors
- 4
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- eye infection
via ChEMBL · EBI
Research
32 papers- [Graze with unusual progress].Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2009
- Allergic contact dermatitis from dibrompropamidine cream.Contact dermatitis · 1989
- Acanthamoeba keratitis.The British journal of ophthalmology · 1987
- Contact allergy to dibrompropamidine cream.Contact dermatitis · 1983
- Local dibrompropamidine in the treatment of burns.British journal of plastic surgery · 1955
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 467.9796500160001
Show 2 more facts
- canonical SMILES
- C1=CC(=C(C=C1C(=N)N)Br)OCCCOC2=C(C=C(C=C2)C(=N)N)Br
- chemical formula
- C₁₇H₁₈Br₂N₄O₂
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Characteristics
- References
Dibrompropamidine is an antiseptic and disinfectant. As dibrompropamidine isethionate, it is used in eyedrops and ointment for the treatment of minor eye and eyelid infections in adults and children. In the UK, such preparations are sold under the brand names Brolene (Aventis Pharma), Golden Eye (Typharm Ltd), and Brulidine (Manx Healthcare).
==Characteristics== Dibrompropamidine is a white or almost white crystalline powder. It is odourless or almost odourless. Dibrompropamidine is freely soluble in water, soluble in glycerol, sparingly soluble in ethanol (96%), and practically insoluble in chloroform, in ether, in liquid paraffin and in fixed oils. ==References==
Excerpted from Wikipedia’s “dibrompropamidine” article, available under the CC BY-SA 4.0 licence.