Also known as dihydroavicine
Dihydrosanguinarine is an alkaloid found in the herbs Corydalis adunca and Lamprocapnos spectabilis. It gets its name from the Sanguinaria canadensis plant in the poppy family Papaveraceae in which it is also found.
Dihydrosanguinarine is an alkaloid found in the herbs Corydalis adunca and Lamprocapnos spectabilis. It gets its name from the Sanguinaria canadensis plant in the poppy family Papaveraceae in which it is also found.
==Biosynthesis== Dihydrosanguinarine is a benzylisoquinoline alkaloid produced in plants from the amino acid tyrosine. A sequence of enzyme-catalysed reactions gives (S)-norcoclaurine which goes through three further transformations to yield (S)-3'-hydroxy-N-methylcoclaurine. (S)-reticuline is made when the enzyme 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase adds a methyl group. Reticuline is a branch point in the biosynthesis: the (R) enantiomer is used to eventually produce morphine, for example in the opium poppy Papaver somniferum while other pathways use the initially-formed (S) isomer leading to sanguinarine via dihydrosanguinarine.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).