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EntityQ421580· pop 17· linked from 641 articles

diphtheria toxin

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Also known as diphtheric toxin

exotoxin

In the Vinony graph

Within Vinony's link graph, diphtheria toxin is referenced by 641 other articles, and connects out to solasonine, glucuronosyltransferase and bacteriophage.

It is catalogued under topics including Bacterial toxins, Diphtheria and Hepatotoxins.

Its subject is documented across 16 Wikipedia language editions.

Protein · UniProt

Diphtheria toxin

Organism
Corynephage omega
Length
560 aa
Molecular mass
60,815 Da
Evidence
4: Predicted

Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to elongation factor 2. Fragment A is responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A

Cleavage on pair of basic residuesDisulfide bondGlycosyltransferaseNADNucleotidyltransferaseSignalToxinTransferase
View on UniProt →

Swiss-Prot (reviewed) · via UniProt

Research

6,936 papers

via PubMed

Wikidata facts

Instance of
protein
Subclass of
exotoxin
Image
PDB 1xdt EBI.jpg
Show 3 more facts
discoverer or inventor
Alexandre Yersin
EC enzyme number
2.4.2.36
Commons category
Diphtheria toxin
Sources (3)

via Wikidata · CC0

Connections

Categories