DKK2
Sign in to saveAlso known as DKK-2, dickkopf WNT signaling pathway inhibitor 2
Dickkopf-related protein 2 is a protein in the Dickkopf family that in humans is encoded by the DKK2 gene.
In the Vinony graph
Within Vinony's link graph, DKK2 is referenced by 3 other articles, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 7 Wikipedia language editions.
Gene data
DKK2- Name
- dickkopf Wnt signaling pathway inhibitor 2
- Type
- protein-coding
- Position
- 106,921,802–107,283,806 (−)
- Aliases
- DKK-2
- Ensembl
- ENSG00000155011
- RefSeq RNA
- NM_014421.3
- RefSeq protein
- NP_055236.1
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
dickkopf Wnt signaling pathway inhibitor 2
- Symbol
- DKK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:106,921,802-107,283,806
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8681
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/27123
- genomic end
- 108204963
- genomic start
- 107842959
- chromosome
- human chromosome 4
- cytogenetic location
- 4q25
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Dickkopf-related protein 2 is a protein in the Dickkopf family that in humans is encoded by the DKK2 gene.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway.
Excerpted from Wikipedia’s “DKK2” article, available under the CC BY-SA 4.0 licence.