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doxefazepam

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EntityQ3714813· pop 11· linked from 637 articles

doxefazepam

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Also known as Doxefazepamum

Doxefazepam (marketed under brand name Doxans) is a benzodiazepine medication. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used therapeutically as a hypnotic. According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic in laboratory animals.

Chemical data

Formula
C17H14ClFN2O3
Molecular weight
348.8 g/mol
IUPAC name
7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-3H-1,4-benzodiazepin-2-one

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
348.068
Show 3 more facts
chemical formula
C₁₇H₁₄ClFN₂O₃
canonical SMILES
C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCO)O)F
Commons category
Doxefazepam
Sources (2)

via Wikidata · CC0

~1 min read

Article

4 sections
Contents
  • Side effects
  • See also
  • References
  • External links

Doxefazepam (marketed under brand name Doxans) is a benzodiazepine medication. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used therapeutically as a hypnotic. According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic in laboratory animals.

It was patented in 1972 and came into medical use in 1984.

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