Structure via PubChem · Public domain (PubChem)
EDANS
Sign in to saveEDANS (5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid) is a donor for FRET-based nucleic acid probes and protease substrates. EDANS is often paired with DABCYL or DABSYL. The combination can be used in enzyme assays. When the two compounds are in close proximity, most of the energy emitted from EDANS will be quenched by DABCYL. However, if the compounds are separated (for example, by substrate cleavage) EDANS will fluoresce, giving an indication of enzyme presence.
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Vinony's link graph records 1 inbound reference to EDANS, and connects out to digital object identifier, chemical formula and molecular biology.
Vinony files it under ECHA InfoCard ID from Wikidata and Fluorescent dyes.
Vinony links it to 7 Wikipedia language editions.
Chemical data
- Formula
- C12H14N2O3S
- Molecular weight
- 266.32 g/mol
- IUPAC name
- 5-(2-aminoethylamino)naphthalene-1-sulfonic acid
- SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCN
- InChIKey
- SJQRQOKXQKVJGJ-UHFFFAOYSA-N
- XLogP
- -1.3
- Polar surface area
- 101 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 266.072513
Show 2 more facts
- chemical formula
- C₁₂H₁₄N₂O₃S
- canonical SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCN
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
EDANS (5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid) is a donor for FRET-based nucleic acid probes and protease substrates. EDANS is often paired with DABCYL or DABSYL. The combination can be used in enzyme assays. When the two compounds are in close proximity, most of the energy emitted from EDANS will be quenched by DABCYL. However, if the compounds are separated (for example, by substrate cleavage) EDANS will fluoresce, giving an indication of enzyme presence.
==See also== Dark quencher
Excerpted from Wikipedia’s “EDANS” article, available under the CC BY-SA 4.0 licence.