EIF4E2
Sign in to saveAlso known as 4E-LP, 4EHP, EIF4EL3, IF4e, eukaryotic translation initiation factor 4E family member 2, h4EHP
gene umano
Gene data
EIF4E2- Name
- eukaryotic translation initiation factor 4E family member 2
- Type
- protein-coding
- Position
- 232,550,633–232,585,201 (+)
- Aliases
- 4E-LP, 4EHP, EIF4EL3, IF4e, h4EHP
- Ensembl
- ENSG00000135930
- RefSeq RNA
- NM_001276336.2, NM_001276337.2, NM_001282958.2, NM_001330201.2, NM_001330202.2
- RefSeq protein
- NP_001263265.1, NP_001263266.1, NP_001269887.1, NP_001317130.1, NP_001317131.1
Enables ubiquitin protein ligase binding activity. Involved in positive regulation of miRNA mediated inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. Part of mRNA cap binding activity complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
translational initiationtranslational initiationnegative regulation of translationmiRNA-mediated gene silencing by inhibition of translationnegative regulation of translational initiationnegative regulation of type I interferon-mediated signaling pathwayrescue of stalled cytosolic ribosomepre-mRNA catabolic process
Molecular function
Pathways
RNA transport - Homo sapiens (human)HIF-1 signaling pathway - Homo sapiens (human)mTOR signaling pathway - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Longevity regulating pathway - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)ISG15 antiviral mechanismAntimicrobial mechanism of IFN-stimulated genesCytokine Signaling in Immune systemImmune System
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 4E family member 2
- Symbol
- EIF4E2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:232,550,633-232,585,201
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein EIF4E2 PDB 2jgb.png
Show 8 more facts
- HomoloGene ID
- 128466
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9470
- genomic end
- 233448354
- genomic start
- 232550659
- chromosome
- human chromosome 2
- cytogenetic location
- 2q37.1
- expressed in
- amniotic fluid
Sources (4)
via Wikidata · CC0