EIF5
Sign in to saveAlso known as EIF-5, EIF-5A, eukaryotic translation initiation factor 5, Eukaryotic initiation factor 5
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene.
Gene data
EIF5- Name
- eukaryotic translation initiation factor 5
- Type
- protein-coding
- Position
- 103,333,544–103,345,025 (+)
- Aliases
- EIF-5, EIF-5A
- Ensembl
- ENSG00000100664
- RefSeq RNA
- NM_001969.5, NM_183004.5
- RefSeq protein
- NP_001960.2, NP_892116.2
Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 5
- Symbol
- EIF5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:103,333,544-103,345,025
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein EIF5 PDB 2g2k.png
Show 9 more facts
- HomoloGene ID
- 49610
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1983
- genomic end
- 103811362
- genomic start
- 103799881
- chromosome
- human chromosome 14
- cytogenetic location
- 14q32.32
- expressed in
- oocyte
- Commons category
- Eukaryotic translation initiation factor 5
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene.
EIF5 is a GTPase-activating protein.
Excerpted from Wikipedia’s “EIF5” article, available under the CC BY-SA 4.0 licence.