Enterotoxine
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An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines. They can be chromosomally or plasmid encoded. They are heat labile (> 60 °C), of low molecular weight and water-soluble. Enterotoxins are frequently cytotoxic and kill cells by altering the apical membrane permeability of the mucosal (epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes the cells to die.
Key facts
- Protein family.Symbol
- Stap_Strp_tox_C
- Protein family.Name
- Staph/Strep enterotoxin, C terminal
- Protein family.image
- PDB 1uns EBI.jpg
- Protein family.caption
- identification of a secondary zinc-binding site in staphylococcal enterotoxin c2: implications for superantigen recognition
- Protein family.Pfam
- PF02876
- Protein family.Pfam_clan
- CL0386
- Protein family.InterPro
- IPR006123
- Protein family.PROSITE
- PDOC00250
- Protein family.SCOP
- 1se3
- Protein family.OPM family
- 364
- Protein family.OPM protein
- 1dyq
via Wikipedia infobox
Article · Nederlands
Een enterotoxine is een virulentiefactor die vrijkomt als het organisme groeit, en dit op de dunne darm inwerkt. Dit leidt meestal tot massieve secretie van water en opgeloste stoffen. Onder andere cholera wordt hierdoor veroorzaakt. Sommige pathogene (ziekteverwekkende) bacteriën produceren virulentiefactoren, extracellulaire proteïnen die helpen bij het in stand houden van de ziekte.
Abstract from DBpedia / Wikipedia · CC BY-SA