Entérotoxine
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An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines. They can be chromosomally or plasmid encoded. They are heat labile (> 60 °C), of low molecular weight and water-soluble. Enterotoxins are frequently cytotoxic and kill cells by altering the apical membrane permeability of the mucosal (epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes the cells to die.
Key facts
- Protein family.Symbol
- Stap_Strp_tox_C
- Protein family.Name
- Staph/Strep enterotoxin, C terminal
- Protein family.image
- PDB 1uns EBI.jpg
- Protein family.caption
- identification of a secondary zinc-binding site in staphylococcal enterotoxin c2: implications for superantigen recognition
- Protein family.Pfam
- PF02876
- Protein family.Pfam_clan
- CL0386
- Protein family.InterPro
- IPR006123
- Protein family.PROSITE
- PDOC00250
- Protein family.SCOP
- 1se3
- Protein family.OPM family
- 364
- Protein family.OPM protein
- 1dyq
via Wikipedia infobox
Article · Français
Une entérotoxine est une substance toxique (toxine) produite par un organisme (en particulier certaines bactéries, telles que le vibrion cholérique responsable du choléra) susceptible de provoquer des troubles intestinaux lors de sa diffusion dans le système digestif.Ces toxines adhèrent à l'épithélium intestinal de l'intestin grêle et empêchent l'absorption des ions Na+ et Cl- favorisant une fuite hydrique (diarrhées...). * Portail de la biologie * Portail de la biochimie
Abstract from DBpedia / Wikipedia · CC BY-SA