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GeneQ17916932· pop 8· linked from 119 articles

Also known as EHK-3, EHK3, EK11, HEK11, EPH receptor A7

Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene.

Gene data

EPHA7
Name
EPH receptor A7
Type
protein-coding
Position
93,240,010–93,419,687 (−)
Aliases
EHK-3, EHK3, EK11, HEK11
RefSeq RNA
NM_001288629.2, NM_001288630.2, NM_001376465.1, NM_001376466.1, NM_001376467.1
RefSeq protein
NP_001275558.1, NP_001275559.1, NP_001363394.1, NP_001363395.1, NP_001363396.1

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].

via MyGene.info

Gene · Ensembl

EPH receptor A7

Symbol
EPHA7
Biotype
Protein coding
Organism
Homo sapiens
Location
6:93,240,010-93,419,687
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein EPHA7 PDB 2REI.png
Show 6 more facts
HomoloGene ID
20935
genomic end
93419559
genomic start
93949738
cytogenetic location
6q16.1
Commons category
EphA7 receptor
Sources (4)

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Article

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Contents
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Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene.

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

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