EPHA7
Sign in to saveAlso known as EHK-3, EHK3, EK11, HEK11, EPH receptor A7
Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene.
Gene data
EPHA7- Name
- EPH receptor A7
- Type
- protein-coding
- Position
- 93,240,010–93,419,687 (−)
- Aliases
- EHK-3, EHK3, EK11, HEK11
- Ensembl
- ENSG00000135333
- RefSeq RNA
- NM_001288629.2, NM_001288630.2, NM_001376465.1, NM_001376466.1, NM_001376467.1
- RefSeq protein
- NP_001275558.1, NP_001275559.1, NP_001363394.1, NP_001363395.1, NP_001363396.1
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
EPH receptor A7
- Symbol
- EPHA7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:93,240,010-93,419,687
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EPHA7 PDB 2REI.png
Show 6 more facts
- HomoloGene ID
- 20935
- exact match
- identifiers.org/ncbigene/2045
- genomic end
- 93419559
- genomic start
- 93949738
- cytogenetic location
- 6q16.1
- Commons category
- EphA7 receptor
Sources (4)
via Wikidata · CC0
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Article
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- Further reading
Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
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