EPHB3

Also known as ETK2, HEK2, TYRO6, EPH receptor B3, EK2

Ephrin type-B receptor 3 is a protein that in humans is encoded by the EPHB3 gene.

Gene data

EPHB3

Name: EPH receptor B3
Type: protein-coding
Aliases: EK2, ETK2, HEK2, TYRO6

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010].

via MyGene.info