epidermal growth factor

Protein · UniProt

Pro-epidermal growth factor

Gene

EGF

Organism

Homo sapiens (Human)

Length

1,207 aa

Molecular mass

133,994 Da

Evidence

1: Evidence at protein level

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941)

• [Progress in human epidermal growth factor research].Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2020
• Epidermal growth factor.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1987
• Epidermal growth factor and related molecules.Lancet (London, England) · 1989
• The epidermal growth factor (EGF).Cancer · 1983
• Epidermal growth factor: biology and mechanism of action.Birth defects original article series · 1980

via PubMed

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via ClinicalTrials.gov