ESCRT
Sign in to saveAlso known as GO:0036452, endosomal sorting complex required for transport, endosomal sorting complexes required for transport
The endosomal sorting complexes required for transport (ESCRT) proteins are part of a pathway inside cells that helps sort and move other proteins. One of their main jobs is to form structures called multivesicular bodies (MVBs) which help sending of certain proteins, especially ones tagged for removal, to compartments in the cell called lysosomes where they get broken down.
Research
2,301 papers- The ESCRT pathway.Developmental cell · 2011
- ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.The Journal of cell biology · 2020
- The many functions of ESCRTs.Nature reviews. Molecular cell biology · 2020
- Triggered recruitment of ESCRT machinery promotes endolysosomal repair.Science (New York, N.Y.) · 2018
- The ESCRT-III complex contributes to macromitophagy in yeast.Traffic (Copenhagen, Denmark) · 2021
via PubMed