Structure via PubChem · Public domain (PubChem)
etizolam
Sign in to saveAlso known as Etilaam, Intas Etilaam, 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine
thumb|Etizolam powder. Pictured is roughly 150 mg; a standard dose is around 1 mg alt=Four blister packs of Etizex brand etizolam tablets|thumb|Etizex brand etizolam tablets Etizolam is a thienodiazepine derivative which is a benzodiazepine analog. The etizolam molecule differs from a benzodiazepine in that the benzene ring has been replaced by a thiophene ring and triazole ring has been fused, making the drug a thienotriazolodiazepine.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443854261
- Drug.IUPAC_name
- 4-(2-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
- Drug.tradename
- Etizest, Etilaam, Etizex, Depas, Sedekopan, Pasaden
- Drug.image
- Etizolam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 150
- Drug.image2
- Etizolam-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.KEGG
- D01514
- Drug.ChemSpiderID
- 3191
- Drug.smiles
- ClC1=CC=CC=C1C2=NCC3=NN=C(C)N3C4=C2C=C(CC)S4
- Drug.StdInChI
- 1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3
- Drug.StdInChIKey
- VMZUTJCNQWMAGF-UHFFFAOYSA-N
- Drug.UNII
- A76XI0HL37
- Drug.CAS_number
- 40054-69-1
- Drug.ATC_prefix
- N05
via Wikipedia infobox
Chemical data
- Formula
- C17H15ClN4S
- Molecular weight
- 342.8 g/mol
- IUPAC name
- 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene
- SMILES
- CCC1=CC2=C(S1)N3C(=NN=C3CN=C2C4=CC=CC=C4Cl)C
- InChIKey
- VMZUTJCNQWMAGF-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 71.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
259 papers- Etizolam.2006
- Etizolam: A rapid review on pharmacology, non-medical use and harms.Drug and alcohol review · 2020
- Etizolam and Its Major Metabolites: A Short Review.Journal of analytical toxicology · 2023
- "Pressed" Etizolam.The Journal of pediatrics · 2021
- Etizolam and Irish drug poisoning deaths.Irish journal of psychological medicine · 2024
via PubMed
~9 min read
Encyclopedic overview
20 sectionsContents
- Medical uses
- Side effects
- Tolerance, dependence and withdrawal
- Pharmacology
- Interactions
- Overdose
- Society and culture
- Brand names
- Legal status
- International drug control conventions
- Australia
- Denmark
- Germany
- Italy
- India
- United States
- Misuse
- See also
- References
- External links
thumb|Etizolam powder. Pictured is roughly 150 mg; a standard dose is around 1 mg alt=Four blister packs of Etizex brand etizolam tablets|thumb|Etizex brand etizolam tablets Etizolam is a thienodiazepine derivative which is a benzodiazepine analog. The etizolam molecule differs from a benzodiazepine in that the benzene ring has been replaced by a thiophene ring and triazole ring has been fused, making the drug a thienotriazolodiazepine.
Although a thienodiazepine, etizolam is clinically regarded as a benzodiazepine because of its mode of action via the benzodiazepine receptor and directly targeting GABAA allosteric modulator receptors.
Excerpted from Wikipedia’s “etizolam” article, available under the CC BY-SA 4.0 licence.