FLT3LG
Sign in to saveAlso known as FL, FLT3L, fms related tyrosine kinase 3 ligand, FLG3L, fms related receptor tyrosine kinase 3 ligand
protein-coding gene in the species Homo sapiens
Gene data
FLT3LG- Name
- fms related receptor tyrosine kinase 3 ligand
- Type
- protein-coding
- Aliases
- FL, FLG3L, FLT3L, IMD125
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011].
via MyGene.info
Gene · Ensembl
fms related receptor tyrosine kinase 3 ligand
- Symbol
- FLT3LG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:49,474,150-49,486,233
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein FLT3LG PDB 1ete.png
Show 5 more facts
- HomoloGene ID
- 48021
- exact match
- identifiers.org/ncbigene/2323
- genomic end
- 49989488
- genomic start
- 49977464
- cytogenetic location
- 19q13.33
Sources (3)
via Wikidata · CC0
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