flurazepam
Sign in to saveFlurazepam (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It produces a metabolite with a long half-life, which may stay in the bloodstream for days. Flurazepam was patented in 1968 and came into medical use the same year. Flurazepam, developed by Roche Pharmaceuticals, was one of the first benzodiazepine hypnotic medications to be marketed.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461102409
- Drug.IUPAC_name
- 7-Chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Drug.image
- Flurazepam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 185
- Drug.image2
- Flurazepam3d.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 140
- Drug.tradename
- Dalmane, Dalmadorm, Fluzepam
- Drug.MedlinePlus
- a682051
- Drug.pregnancy_category
- X (Contraindicated in pregnancy)
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.metabolites
- N-desalkylflurazepam (active metabolite)
- Drug.elimination_half life
- 2.3 hours N-desalkylflurazepam: 47–100 hours
- Drug.excretion
- Kidney
- Drug.IUPHAR_ligand
- 7188
via Wikipedia infobox
Research
1,210 papers- Flurazepam hydrochloride.Clinical pharmacology and therapeutics · 1975
- Flurazepam hydrochloride, a benzodiazepine hypnotic.Annals of internal medicine · 1975
- Flurazepam (Dalmane).The Medical letter on drugs and therapeutics · 1975
- Quazepam and flurazepam: differential pharmacokinetic and pharmacodynamic characteristics.The Journal of clinical psychiatry · 1991
- Flurazepam and insomnia.Science (New York, N.Y.) · 1979
via PubMed
Article
11 sectionsContents
- Medical uses
- Side effects
- Tolerance, dependence and withdrawal
- Contraindications and special caution
- Elderly
- Pharmacology
- Misuse
- Legal status
- See also
- References
- External links
Flurazepam (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It produces a metabolite with a long half-life, which may stay in the bloodstream for days.
Flurazepam was patented in 1968 and came into medical use the same year. Flurazepam, developed by Roche Pharmaceuticals, was one of the first benzodiazepine hypnotic medications to be marketed.