fluticasone/salmeterol
Sign in to saveAlso known as salmeterol / fluticasone propionate, fluticasone / salmeterol, salmeterol / fluticasone, fluticasone-salmeterol
Fluticasone/salmeterol, sold under the brand name Advair among others, is a fixed-dose combination medication containing fluticasone propionate, an inhaled corticosteroid; and salmeterol, a long-acting beta2‑adrenergic agonist. It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It is used by inhaling the medication into the lungs.
Key facts
- Drug.verifiedrevid
- 447411501
- Drug.type
- combo
- Drug.image
- Fluticasone propionate and salmeterol.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225
- Drug.caption
- Fluticasone propionate (top) and salmeterol (bottom)
- Drug.component1
- Fluticasone propionate
- Drug.class1
- Glucocorticoid
- Drug.component2
- Salmeterol
- Drug.class2
- Long-acting beta-adrenoceptor agonist
- Drug.tradename
- Advair, Seretide, Cyplos, others
- Drug.MedlinePlus
- a699063
- Drug.DailyMedID
- Fluticasone and salmeterol
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- Inhalation
- Drug.ATC_prefix
- R03
- Drug.ATC_suffix
- AK06
- Drug.legal_AU
- S4
via Wikipedia infobox
Research
1,582 papers- Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD.The New England journal of medicine · 2016
- Budesonide-Formoterol Metered-Dose Inhaler vs Fluticasone-Salmeterol Dry-Powder Inhaler.JAMA internal medicine · 2025
- Salmeterol-Fluticasone: The Role Revisited.The Journal of the Association of Physicians of India · 2022
- Fluticasone Propionate/Salmeterol MDPI (AirDuo RespiClick(®)): A Review in Asthma.Clinical drug investigation · 2018
- Salmeterol/fluticasone propionate: a review of its use in asthma.Drugs · 2009
via PubMed
Wikidata facts
- Subclass of
- combination drug
- Has part
- fluticasone
- Mass
- 915.456688
- Has use
- medication
Show 4 more facts
- chemical formula
- C₅₀H₆₈F₃NO₉S
- canonical SMILES
- CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF.C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
- isomeric SMILES
- CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF.C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
- medical condition treated
- respiratory disease
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- Society and culture
- Legal status
- Generic equivalents
- Civil settlements
- References
Fluticasone/salmeterol, sold under the brand name Advair among others, is a fixed-dose combination medication containing fluticasone propionate, an inhaled corticosteroid; and salmeterol, a long-acting beta2‑adrenergic agonist. It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It is used by inhaling the medication into the lungs.
Common side effects include thrush, headache, and cough. Serious side effects may include worsening asthma, anaphylaxis, seizures, and heart problems. Safety in pregnancy and breastfeeding is unclear. Fluticasone, a corticosteroid, works by decreasing inflammation while salmeterol, a long-acting beta-adrenoceptor agonist (LABA), works by activating beta-2 adrenergic receptors.
Excerpted from Wikipedia’s “fluticasone/salmeterol” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0