Structure via PubChem · Public domain (PubChem)
bamifylline
Sign in to saveBamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.
Chemical data
- Formula
- C20H27N5O3
- Molecular weight
- 385.5 g/mol
- IUPAC name
- 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
- SMILES
- CCN(CCN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CC3=CC=CC=C3)CCO
- InChIKey
- VVUYEFBRTFASAH-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 81.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Airway obstruction
via ChEMBL · EBI
Research
69 papers- Severe bronchial asthma improved on bamifylline. Case report and review.Respiration; international review of thoracic diseases · 1994
- [Bamifylline induced exanthema].Annales de dermatologie et de venereologie · 1991
- Xanthines and Phosphodiesterase Inhibitors.Handbook of experimental pharmacology · 2017
- [Bronchial dysreactive syndromes: bamifylline].Archivio Monaldi per le malattie del torace · 1989
- Evidence of pulmonary tropism of bamifylline and its main active metabolite.Arzneimittel-Forschung · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 385.211
Show 4 more facts
- chemical formula
- C₂₀H₂₇N₅O₃
- canonical SMILES
- CCN(CCN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CC3=CC=CC=C3)CCO
- subject has role
- bronchodilator
- Commons category
- Bamifylline
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 459517599 | ImageFile = Bamifylline.svg | ImageClass = skin-invert-image | ImageAlt = Skeletal formula of bamifylline | ImageFile1 = Bamifylline 3D spacefill.png | ImageClass1 = bg-transparent | ImageAlt1 = Space-filling model of the bamifylline molecule | PIN = 8-Benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione | OtherNames =
| Section1 =
Excerpted from Wikipedia’s “bamifylline” article, available under the CC BY-SA 4.0 licence.