FOXP1

Also known as 12CC4, HSPC215, MFH, QRF1, hFKH1B, forkhead box P1

Forkhead box protein P1 is a protein that in humans is encoded by the FOXP1 gene. FOXP1 is necessary for the proper development of the brain, heart, and lung in mammals. It is a member of the large FOX family of transcription factors.

Gene data

FOXP1

Name: forkhead box P1
Type: protein-coding
Aliases: 12CC4, HSPC215, MFH, QRF1, hFKH1B

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image: FOXP1.png

Show 5 more facts

HomoloGene ID: 136512
exact match: identifiers.org/ncbigene/27086
cytogenetic location: 3p13
genomic start: 70954693
genomic end: 71583978

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Contents

Function
See also
References
Further reading
External links

== Function == This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.