FOXP4
Sign in to saveAlso known as hFKHLA, forkhead box P4
Forkhead box protein P4 is a protein that in humans is encoded by the FOXP4 gene.
Gene data
FOXP4- Name
- forkhead box P4
- Type
- protein-coding
- Position
- 41,546,341–41,602,384 (+)
- Aliases
- hFKHLA
- Ensembl
- ENSG00000137166
- RefSeq RNA
- NM_001012426.2, NM_001012427.2, NM_001405824.1, NM_001405825.1, NM_001405826.1
- RefSeq protein
- NP_001012426.1, NP_001012427.1, NP_001392753.1, NP_001392754.1, NP_001392755.1
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
forkhead box P4
- Symbol
- FOXP4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:41,546,341-41,602,384
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 12536
- genetic association
- prostate cancer
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/116113
- genomic end
- 41570122
- genomic start
- 41546381
- chromosome
- human chromosome 6
- cytogenetic location
- 6p21.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Forkhead box protein P4 is a protein that in humans is encoded by the FOXP4 gene.
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. It also is a major factor in developing Long COVID as such, increasing the chances of developing the little-understood syndrome 1.6 fold, a finding which has major implications for COVID-19 pandemic research.
Excerpted from Wikipedia’s “FOXP4” article, available under the CC BY-SA 4.0 licence.