fremanezumab
Sign in to saveAlso known as Ajovy, TEV-48125, fremanezumab-vfrm
Fremanezumab, sold under the brand name Ajovy, is a medication used to prevent migraines. It is given by subcutaneous injection (injection under the skin).
Key facts
- Drug.O
- 2016
- Drug.type
- mab
- Drug.image
- AJOVY.jpg
- Drug.caption
- A Norwegian syringe of fremanezumab
- Drug.mab_type
- mab
- Drug.source
- zu
- Drug.target
- Calcitonin gene-related peptide (CGRP) α, β
- Drug.tradename
- Ajovy
- Drug.MedlinePlus
- a618053
- Drug.DailyMedID
- Fremanezumab
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- Subcutaneous
- Drug.class
- Calcitonin gene-related peptide antagonist
- Drug.ATC_prefix
- N02
- Drug.ATC_suffix
- CD03
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_CA_comment
- / Schedule D
via Wikipedia infobox
Medication
- Generic name
- Fremanezumab-Vfrm
- Brand names
- Ajovy
- Drug class
- Calcitonin gene-related peptide (CGRP) antagonists
- Active ingredients
- fremanezumab
- Route
- Subcutaneous
- Dosage form
- Auto-Injector, Prefilled Syringe
- Type
- Human Prescription Drug
- Manufacturer
- Teva Pharmaceuticals USA, Inc.
Indications: 1 INDICATIONS AND USAGE AJOVY is indicated for: the preventive treatment of migraine in adults, and the preventive treatment of episodic migraine in pediatric patients who are 6 to 17 years of age and who weigh 45 kg or more. AJOVY is a calcitonin gene-related peptide antagonist indicated for: th… (per FDA label)
Clinical Trials
28 registered- UNKNOWNQST, Blink Reflex and Nociceptive Flexion Reflex in HeadacheUniversity of Liege · NCT04585698
- NAUNKNOWNMedicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind StudyManhattan Beach Orthodontics · NCT04547179
- RECRUITINGFremanezumab for the Prevention of Menstrually-related Migraine AttacksInsel Gruppe AG, University Hospital Bern · NCT06659120
- PHASE3COMPLETEDA Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and AdolescentsTeva Branded Pharmaceutical Products R&D LLC · NCT04530110
- PHASE3COMPLETEDEfficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of MigraineTeva Branded Pharmaceutical Products R&D, Inc. · NCT02638103
- PHASE3COMPLETEDA Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period on Efficacy and Safety of Fremanezumab in Chinese Adults With MigraineTeva Branded Pharmaceutical Products R&D, Inc. · NCT05458011
~2 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- History
- References
Fremanezumab, sold under the brand name Ajovy, is a medication used to prevent migraines. It is given by subcutaneous injection (injection under the skin).
The most common side effect is pain and redness at the site of injection. Other side effects include allergic reactions. It is a calcitonin gene-related peptide antagonist.
Excerpted from Wikipedia’s “fremanezumab” article, available under the CC BY-SA 4.0 licence.