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EntityQ99388898· pop 10· linked from 58 articles

zavegepant

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Also known as vazegepant, BHV-3500, BMS-742413, N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide

Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. Zavegepant is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer.

Key facts

Drug.image
Zavegepant.svg
Drug.image_class
skin-invert-image
Drug.tradename
Zavzpret
Drug.DailyMedID
Zavegepant
Drug.routes_of_administration
Nasal
Drug.class
Calcitonin gene-related peptide receptor antagonist
Drug.ATC_prefix
N02
Drug.ATC_suffix
CD08
Drug.legal_US
Rx-only
Drug.index2_label
as HCl
Drug.CAS_number
1337918-83-8
Drug.CAS_number2
1414976-20-7
Drug.PubChem
53472683
Drug.PubChem2
134819878
Drug.DrugBank
DB15688
Drug.ChemSpiderID
30814207
Drug.UNII
ODU3ZAZ94J
Drug.UNII2
000QCM6HAL

via Wikipedia infobox

Wikidata facts

Mass
638.3692873320001
Show 5 more facts
canonical SMILES
CC1=CC(=CC2=C1NN=C2)CC(C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O
isomeric SMILES
CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O
Commons category
Zavegepant
subject has role
active ingredient
chemical formula
C₃₆H₄₆N₈O₃
Sources (1)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Medical uses
  • References
  • Further reading
  • External links

Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. Zavegepant is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer.

The most common adverse reactions include taste disorders, nausea, nasal discomfort, and vomiting.

Excerpted from Wikipedia’s “zavegepant” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0