Structure via PubChem · Public domain (PubChem)
FV-100
Sign in to saveAlso known as FV100, FV 100, cf-1743, cf1743, cf 1743
FV-100, also known as Cf1743, is an orally available nucleoside analogue drug with antiviral activity. It may be effective against shingles.
Chemical data
- Formula
- C22H26N2O5
- Molecular weight
- 398.5 g/mol
- IUPAC name
- 3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-2-one
- SMILES
- CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)[C@H]4C[C@@H]([C@H](O4)CO)O
- InChIKey
- MFGSDSRTGUVZQG-DFQSSKMNSA-N
- XLogP
- 3.5
- Polar surface area
- 91.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 398.184
Show 3 more facts
- chemical formula
- C₂₂H₂₆N₂O₅
- isomeric SMILES
- CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)[C@H]4C[C@@H]([C@H](O4)CO)O
- canonical SMILES
- CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)C4CC(C(O4)CO)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Clinical trials
- References
FV-100, also known as Cf1743, is an orally available nucleoside analogue drug with antiviral activity. It may be effective against shingles.
It was discovered in 1999 in the laboratories of Prof Chris McGuigan, Welsh School of Pharmacy and Prof. Jan Balzarini, Rega Institute, Leuven, Belgium.
Excerpted from Wikipedia’s “FV-100” article, available under the CC BY-SA 4.0 licence.